Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors.

Ganghammer, S, Gutjahr, J, Hutterer, E, Krenn, PW, Pucher, S, Zelle-Rieser, C, Jöhrer, K, Wijtmans, M, Leurs, R, Smit, MJ, Gattei, V, Greil, R, Hartmann, TN.

http://www.ncbi.nlm.nih.gov/pubmed/26589908